I suffer from a physical disability and no longer have the use of my legs.
I am so sorry to hear about that. If you don't mind me asking, have you found any trouble with daily living? Such as any impairments you may have?
Unfortunately, yes. I have adaptions to my house to make things a little easier, but it's really just not the same. It's difficult to go from full use of my limbs to nothing.
I had a very close friend of mine who was disabled and she had difficulty in mobility, either congenital or an acquired problem. It was pretty tough for her
I think psychologically it can be tough. As a very proud person myself, I struggle to ask others for help, but these days I have no choice. I lost not only my legs, but my dignity, too, or so it feels sometimes.
I can only imagine how difficult that must be for you. I even know some people who have lost their upper or lower limbs, resulting in the damage of their organs.
It's completely life changing. I have an ex veteran friend who lost his arm in Afghanistan. It ruined him.
It's very heartbreaking to see that happen. It can even limit a person's dexterity or stamina.
Absolutely, we have to make adaptions for almost everything. You can feel a burden at times, even though people are genuinely helpful and accepting. 
I agree. The modern age of medicine allowed for improvements in making sure you get the best and most help you can get.