Science fiction has been described as the literature of ideas.
I agree, sci-fi is one of the most inventive and imaginative genres of literature. 
I like that It usually avoids the supernatural
Yes, good science fiction usually utilizes very good science and mixes in unique ideas to alter the story. I personally enjoy forward-looking science fiction. 
Much of the best was written following the scientific revolution and major discoveries in astronomy, physics, and mathematics.
I agree, some of my favorite science fiction literature is from Asimov.
He wrote so much!   More than 500 books and an estimated 90,000 letters and postcards.
He has influenced the entire modern genre in many ways.